Pregnanediol Excretion

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Excretion of Sodium Pregnanediol Glucuronidate

Venning and Browne (1 to 7) have shown that sodium pregnanediol glucuronidate is excreted in urine of human pregnancy in concentrations which become increasingly higher as gestation approaches term. Although this demonstration has been repeatedly confirmed (8 to 16), relatively few workers have studied the precise levels and ranges of normal excretion, or have secured long-continued records of ...

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The Excretion of Pregnanediol and 17-Ketosteroids during the Menstrual Cycle in Benign Hirsutism.

In 1949 Koets reported a variation in the urinary 1 7-ketosteroid excretion occurring during the menstrual cycle of women with benign hirsutism, the maximal excretion being at, or about, the presumed time of ovulation. It has been established that in normal women there is little or no cyclical fluctuation in the excretion of 17-ketosteroids (Werner, 1941; Patterson, McPhee, and Greenwood, 1942;...

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Comparison of methods for pregnanediol determination.

A gas chromatographic method of pregnanediol determination has been carried out on 24-hr. urine specimens collected during various phases of the menstrual cycle and during pregnancy. Pregnanediol values were correlated with endometrial histology and cycle day in nonpregnant subjects, and with duration of gestation during pregnancy. Determinations were performed on free pregnanediol and on the a...

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Rapid analysis of pregnanediol in pregnancy urine.

A simple, inexpensive, and rapid method for the determination of pregnanediol in pregnancy urine by gas liquid chromatography is described. Automatic injection of the samples into the gas chromatograph allows up to 36 samples to be run overnight thus saving valuable technical time.The method described can easily be adopted for use in a routine steroid laboratory. The results obtained by this me...

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Enzymatic Hydrolysis of Urinary Sodium Pregnasediol Glucuronidate to Free Pregnanediol*

The available evidence suggests that most of the steriod hormone endproducts which are eliminated from the body by way of the urine are conjugated with an inorganic or organic acid. This conjugation presumably facilitates their transportation and excretion by rendering them soluble in water or urine. Examples of such conjugated steroids which have been isolated from urine as sulfates are andros...

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ژورنال

عنوان ژورنال: BMJ

سال: 1939

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.1.4093.1226